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When do you think anti-aging would be around?

aging upload nano tech ai moores law

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48 replies to this topic

#21
omega_tyrant

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Well they reckon that once we cure the usual reasons for death you will still hit a radiation particle buildup in the body and brain after 3000 years.


What? Who are "they?" Do you have a source for this?

#22
castiel

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Well they reckon that once we cure the usual reasons for death you will still hit a radiation particle buildup in the body and brain after 3000 years. However, I suppose if they figure out a way to transfer consciousness then that need not be an issue. All the more reason to inhabit every rock in the solar system population is going to go nuts.

 

Some organisms have been found to live over 4000 years.  Why would this specifically affect humans?  Also the body is constantly taking in and expelling matter, why would radioactive particles,specifically,buildup?


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#23
Rolletroll

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If consciousness can be moved or recreated in another brain, Death could be a long but finished state on a cosmic scale. My brain and my mind would be recreated after an incredible amount of time, when the chance that created me the first time will happen again.



#24
caltrek

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It seems to me that half of what is being discussed is addressed by the article I have linked below:

 

http://ww2.kqed.org/...g-research-mice

 

Excerpts to give you the gist are as follows:

 

 

Researchers announced this past week that they’ve been able to reverse the aging process in mice, using a chemical that in one week made two-year-old mice tissue resemble tissue of six-month-old mice. In human years, that’s as if a 60-year-old’s cells became more like the cells of a 20-year-old.

 

In a paper published in the journal Cell, lead investigator Dr. David Sinclair, professor of genetics at Harvard Medical School, and his colleagues report that a compound naturally made by young cells called NAD (nicotinamide adenine dinucleotide) was able to revitalize older cells and make them youthful and energetic again.

 

The study, a joint project between Harvard Medical School; the National Institute on Aging; and the University of New South Wales, Sydney, found that the cell nucleus and the mitochondria (the cell’s energy source) stop communicating as we age. Over time this loss of communication reduces the cell’s ability to make energy, and aging accelerates. But boosting a cell’s NAD levels, which decrease with age, helps restore communication.

 

“The aging process we discovered is like a married couple — when they are young, they communicate well, but over time, living in close quarters for many years, communication breaks down,” said Sinclair. “And just like with a couple, restoring communication solved the problem.”

 

Dr. Ana Gomes, a postdoctoral scientist in the Harvard lab, found that by administering a compound that cells transform into NAD, the broken network can be repaired and communication and mitochondrial function rapidly restored. If the compound was given early enough, some aspects of the aging process could be reversed. She told the BBC that the research group wants to begin clinical trials in 2015.

 

As to how AI might fit into all of this, that is way over my head.  There are simply too many variables at work for me to keep track.  Breakthroughs in AI will interact with breakthroughs in medicine and the understanding of human biology.  The mixture that will result seems too hard for me to predict.


The principles of justice define an appropriate path between dogmatism and intolerance on the one side, and a reductionism which regards religion and morality as mere preferences on the other.   - John Rawls


#25
alice123

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Well, aging has become a natural phenomenon and it is generally characterized by the physical, psychological and social changes in an individual over time. This can take place around the age of 40. However, there is a lot you can do to prevent aging including your diet, exercises, home remedies and lot more. Also, you can visit the ink below to get the best tips to prevent aging:

https://sites.google...eventantiageing



#26
caltrek

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Here is another article relevant to the subject:

 

https://www.fastcoex...u-feeling-young

 

 

 

The FDA doesn’t recognize aging itself as a condition, so, instead, companies like Sirtris and GSK are are taking scientific findings about how we age and translating them into drugs that treat specific age-related diseases. The issue is that the clinical trials involved in doing this can take more than a decade, and even then that is no guarantee a drug will be approved. The result has been that, though scientists have made major strides in understanding how and why we age and demonstrating that this aging can be delayed, they’ve so far seen few results in translating their work to help people.

 

…sirtuins, a group of enzymes involved in cell metabolism and energy production that are common to a wide range of living organisms. Researchers have found that boosting the activity of sirtuins, which is sometimes done by calorie restriction diets, can extend lifespan of yeasts, worms, mice, and other animals. Efforts to develop a drug that can have the same effect, without the lack of calories, have been going on for the last two decades, including at Sirtris and GlaxoSmithKline. There are also natural compounds that elevate sirtuins—one is resveratrol, which is already sold as a dietary supplement today. Another is called NAD.

 

NAD—Nicotinamide adenine dinucleotide—is one of the most compelling bits of chemistry related to aging. Its presence in the body is directly correlated with the passage of time: An elderly man will have about half the levels of NAD is his body as a young person. There’s no amount of healthy eating or exercise that can stop the decline. But in a scientific paper published in 2013 that generated headlines about "reversing aging," Harvard’s Sinclair showed that after a week of giving two-year-old mice a boost of NAD, their tissues looked more like six-month-old mice.

 

Elysium’s pill is an attempt to replicate that process naturally in humans. It contains the building blocks of NAD, so the body can easily absorb the smaller molecules and synthesize its own. The pill also contains pterostilbene, a compound, that is a close relative of resveratrol, but which Guarente says is potentially more potent and effective.

 

Its products will only be sold on its website, where Elysium can control more nuanced messaging than on store shelves. Branding, trust, and scientific expertise are what the team hopes differentiates them from the faceless companies that line Whole Foods’ shelves. At the most basic level, that means trust that the pill contains what it says it contains, but also beyond that, trust that it is doing a person any good.

 

"There has been an explosion of science in the field of aging. And I think the public doesn’t really realize how far aging research has come. We have a lot of ideas about the mechanisms of aging, and tons and tons of pathways that can be optimized, tweaked, or activated to possibly extend lifespan," says Stanford University aging researcher Stuart Kim…"I think the public is probably about 30 years behind our thinking about aging. It’s as if we thought about cancer in the way we did in 1960.

 

 

You folks in your thirties are hoping for dramatic anti-aging breakthroughs to extend your lives.  I am in my sixties, yet also still hopeful for such breakthroughs from which I can benefit.  Part of what I would like to see are methods and procedures that are affordable to all. So the idea of relatively cheap  but effective food supplements is pretty much in the too good to be true range. Still, one can always hope.


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The principles of justice define an appropriate path between dogmatism and intolerance on the one side, and a reductionism which regards religion and morality as mere preferences on the other.   - John Rawls


#27
Breezymadi

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In my point of view anti aging means always looks young! The key is not so much to cover up the wrinkles but increase your levels of good fats LIKE fish oil, borage oil, raw virgin coconut in the diet internally to reduce them altogether. Along with this we can use the dermalmd anti aging serum to removal the fined lines in my face. It works Nice!



#28
Yuli Ban

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In my point of view anti aging means always looks young! The key is not so much to cover up the wrinkles but increase your levels of good fats LIKE fish oil, borage oil, raw virgin coconut in the diet internally to reduce them altogether. Along with this we can use the dermalmd anti aging serum to removal the fined lines in my face. It works Nice!

Always looking young isn't the same as always being  young.

 

There are some vain 70-year-olds who look about 30. 

A google search brings up this lady:

q.png

 

 

Outward appearances, however, mean little if your insides are still aging as normal. I could look 25 years old— but if I'm actually 75, my body's gonna let me know. 

Anti-aging implies the whole aging process— inside, outside, micro and macro level— has been halted and even reversed. In which case, if I were 75 but used anti-aging biotechnology to look 25 again, my whole body basically reverts to that of a 25-year-old. My organs are much healthier, my blood is youthful, my mind is quick, my bones are thick and strong, and I don't need any special oils or serums to keep wrinkles away— that just happens naturally, as 98% of 25-year-olds don't have wrinkles (the 2% who do either: abuse hard drugs; have a bizarre genetic disorder, or; experienced ultra-extreme stress).

 

One session of anti-aging biotech brings me back youthful vitality of a 25-year-old, meaning that it will take roughly 50 years for me to "look" like a 75-year-old. And I can keep reverting my age as many times as I please, essentially meaning I never reach biological 75 ever again. Anti-aging creams and surgery, however, gives you temporary outward youth. If a 75-year-old stopped applying these creams, within a few weeks, they'd "look" 75 again. Not to mention, they'd never stop "being" biologically 75 beneath their skin anyway.


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#29
Zeitgeist123

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Sometimes, I'd like to think the panacea of all anti-aging cures will arrive in the form of a very last-minute injection to my arm as I lie in my deathbed, mere moments from finally falling into the cold abyss of death.

 

Life has a way of turning out in the way you least expect it.

it could also be that the reverse-aging injection hits the market a week after you died.


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#30
Raklian

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Sometimes, I'd like to think the panacea of all anti-aging cures will arrive in the form of a very last-minute injection to my arm as I lie in my deathbed, mere moments from finally falling into the cold abyss of death.

 

Life has a way of turning out in the way you least expect it.

it could also be that the reverse-aging injection hits the market a week after you died.

 

 

Yep, it can go either way. Life is that cruel - it does not discriminate.


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#31
kjaggard

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I think drugs and therapies will only slow the processes down a bit (rough guess, about 7% maximum). What I feel will likely be the first steps toward a more longterm solution is likely to be transplantations of younger versions of your own body parts. And the recovery time and relearning processes will be months.

 

I think of it like this. we need to be able to print the scaffolding of an adult organ or limb, hold it in an artificial womb, and permeate it with cloned youthful stemcells and let them become a complete youthful limb/organ. then transplant it alongside the original where possible and allow the body to begin using it before removing the older one. Limbs and skeletal structures may end up just being removed and replaced.

 

at first recovery times and prospects will be much like transplant and radical surgical interventions. Often the nerves need to regrow or repair themselves and have some degree of scarring that can result in decreased function or pain. as we resolve some of these through practice and technique, outcomes will improve.

 

We'll have to start with the largely cosmetic and then gradually work our way into the more complex integrated systems before we move into life support, endocrine and immune systems.

 

there are some beginning steps for some of this. I still think the bioreactor for growing replacement parts and connection of nerves are going to be some of the hardest to get right.

 

that and the somewhat traumatic nature of major transplant surgery make what I see as the likely truth of extended lifespans a bit more scarring than the pil and shot dreams so many people have.

 

eventually I could imagine adapters for connection of nerves and circulation making the process easier and faster, you just grow the limbs or organs with adapted ends that hook up to the adapters on the human body, making it a bit more plug and play. And ultimately I can imagine a who body being possible.

 

But that still leaves brain aging. and solutions to that may be trickier than we realize.

 

Depending on what we learn about brain and longevity I suspect we might get to a place of the first 170 year old by 2117. But I feel like past that point we start making gambles as to whether the replacement brain pieces start to mean that there is no certainty the same consciousness is looking out through the eyes of the subject.


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#32
Sciencerocks

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For A poor fucker like me it probably won't be around at all for a few hundred years.


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#33
Alislaws

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For A poor fucker like me it probably won't be around at all for a few hundred years.

 

If you move to a country with socialized medicine (i think you are in the US?) you might be able to get it, if there is an organization responsible for your medical treatment, they would save a lot of money keeping you in your 20s (where problems are few) rather than letting you age to your 70s (when, unless you are lucky you'll be in and out of medical care pretty regularly, and probably be on some medications) 

 

I think in the future in most sensible countries, the difference between rich and poor (in terms of ageing) will be rich people age till they're 30 then reset to 20 again, while poor people age till they are 50 then the government pays to reset them to 20 to prevent them becoming a burden on the state healthcare. 


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#34
Alice Tepes

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For A poor fucker like me it probably won't be around at all for a few hundred years.

 

If you move to a country with socialized medicine (i think you are in the US?) you might be able to get it, if there is an organization responsible for your medical treatment, they would save a lot of money keeping you in your 20s (where problems are few) rather than letting you age to your 70s (when, unless you are lucky you'll be in and out of medical care pretty regularly, and probably be on some medications) 

 

I think in the future in most sensible countries, the difference between rich and poor (in terms of ageing) will be rich people age till they're 30 then reset to 20 again, while poor people age till they are 50 then the government pays to reset them to 20 to prevent them becoming a burden on the state healthcare. 

 

agreed, this is one of the many problems that capitalism will face in the near future along with automation. also i know its convenient to use years to equate how much a body has aged that is not entirely an accurate way of measuring senescence.


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#35
Roh234

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I wouldn't expect anything till 2050. There's still so much we don't know, new pathways being discovered, genes interacting in ways we never thought before. Each of these things would need a manual experiment and then we could try. I do subscribe to the SENS model, however they are too optimistic Aging is beatable.


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#36
RaichuXU

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Well if brain uploading comes before anti aging then you could probably transfer your consciousness into a different body?

#37
Alislaws

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Alice Tepes: <The rich/poor divide on anti aging treatments>  is one of the many problems that capitalism will face in the near future along with automation. also i know its convenient to use years to equate how much a body has aged that is not entirely an accurate way of measuring senescence.

 

True, my bad, please assume when i mentioned an age i meant "at a level of age related deterioration similar to an average untreated person of X years"

 

 

I wouldn't expect anything till 2050. There's still so much we don't know, new pathways being discovered, genes interacting in ways we never thought before. Each of these things would need a manual experiment and then we could try. I do subscribe to the SENS model, however they are too optimistic Aging is beatable.

 

I don't know, we're seeing more and more CRISPR therapies which have had great results in mice etc. moving to human trials, and it only takes one to work well, and people would pour billions into research to create the second one, or the third one etc. so its possible funding and interest will take off significantly in the next 10 years. I think a lot of the Sens foundation predictions are based on the idea that after the first workable anti-aging therapy is found, interest and funding will skyrocket compared to today's levels. 

 

 

Well if brain uploading comes before anti aging then you could probably transfer your consciousness into a different body?

 

Obviously no one knows how effective anti aging therapies in development now will be, but no one is even close to understanding how the mind works, let alone how to transfer it into a non-biological medium, so i'd say we are much more likely to see anti-aging therapies before we see any kind of mind uploads. i'd be surprised to see mind uploads developed by humans before at least 2100.

 

There is a guy scheduled to have a head transplant in December though so a physical brain transplant may not be a crazy distance away.

 

Personally I'm hoping one day, when my body gives out, i will be able to have my brain transferred into a machine (for life support) then it will be hooked up to computers, allowing me to live in VR, and then i can have a receiver/transmitter put in a body, where the brain should be and i can control it remotely. This would allow me to live in the real world, but be able to re-spawn when i died. 

 

If anti aging is a thing before then, then my body will never give out, so no need. 

 

The artificial remote controlled body would ideally be an enormous battle robot.  :biggrin:


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#38
victoria

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I start using anti aging serum just years back.my friend told abt dermalmd wrinkle free serum.Great product! I like dermalmd serum better than other products.Smells wonderful. Feels nice on my skin.



#39
Raklian

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I start using anti aging serum just years back.my friend told abt dermalmd wrinkle free serum.Great product! I like dermalmd serum better than other products.Smells wonderful. Feels nice on my skin.

 

This post suspiciously smells like an ad spam. What do you guys think?

 

Victoria only has one post.


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#40
Maximus

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I start using anti aging serum just years back.my friend told abt dermalmd wrinkle free serum.Great product! I like dermalmd serum better than other products.Smells wonderful. Feels nice on my skin.

 

This post suspiciously smells like an ad spam. What do you guys think?

 

Victoria only has one post.

 

 

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