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Tell me something new


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15 replies to this topic

#1
Hyndal_Halcyon

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I've been a futurist since 7th grade and now that I'm about to turn 20 this year, I'm getting bored of Orion's arm, Sci-tech daily, singularity hub, livescience, sciencedaily, future wiki, and a ton of other stuffs. Clearly, I've overdone my hobby and I can't help but think there's nothing more than just, you know. Quantum computing, gene editing, spacetime engineering, and mind uploading. Or is it?


As you can see, I'm a huge nerd who'd rather write about how we can become a Type V civilization instead of study for my final exams (gotta fix that).

But to put an end to this topic, might I say that the one and only greatest future achievement of humankind is when it finally becomes posthumankind.


#2
Jakob

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I've been a futurist since 7th grade and now that I'm about to turn 20 this year, I'm getting bored of Orion's arm, Sci-tech daily, singularity hub, livescience, sciencedaily, future wiki, and a ton of other stuffs. Clearly, I've overdone my hobby and I can't help but think there's nothing more than just, you know. Quantum computing, gene editing, spacetime engineering, and mind uploading. Or is it?

http://www.futuretim...e-jakobs-canon/ maybe? If you're interested in something a bit more tongue in cheek.


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#3
zEVerzan

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What about a future where humanity's galaxy-spanning interstellar territory was once unified and advanced, but the difficulty of long-range communication caused it to eventually fracture into many thousands of puny local interstellar territories.

 

Nemo Ramjet's All Tomorrows and Asimov's Foundation are good reads and have sort of inspired a lot of my more recent visions of the future. Say what you will about some kind of grand unified human-descended galactic empire, but nothing lasts forever. Even something run by a vast and powerful AI will become old and hard to maintain.

 

Anyway, once an interstellar empire ceases to be unified anything is fair game in terms of culture and technology from then on. Former colonies could become unsustainable, regress, be isolated and develop for thousands of years on their own and only be found by some separate hegemon from a nearby star.

 

The idea of a galaxy eternally saturated with highly divergent and isolated humans is something I really love right now and it's kind of the basis for a story I'm writing.


I always imagined the future as a time of more reason, empathy, and peace, not less. It's time for a change.
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#4
Raklian

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I've been a futurist since 7th grade and now that I'm about to turn 20 this year, I'm getting bored of Orion's arm, Sci-tech daily, singularity hub, livescience, sciencedaily, future wiki, and a ton of other stuffs. Clearly, I've overdone my hobby and I can't help but think there's nothing more than just, you know. Quantum computing, gene editing, spacetime engineering, and mind uploading. Or is it?

 

How about you delve into aging reversal? It's about to become a real thing.


What are you without the sum of your parts?

#5
wjfox

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It's about to become a real thing.

 

 

It is?



#6
Raklian

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It's about to become a real thing.

 

 

It is?

 

 

Only the senolytics part, for now. There are already human trials for drugs that clear senescent cells from our bodies.

 

It's one of the purported seven types of damages that give rise to aging of the human body according to SENS' definition of aging. Once we succeed in clearing senescent cells, we're effectively solving 1/7th of the hard problem of aging reversal.

 

Here's an excerpt from Fight Aging! website -

 


 

What is the state of progress towards SENS treatments to reverse aging?

 

The following timeline references some of the important developments and advances in rejuvenation biotechnology from recent years, from the slow and incremental start to the present more rapid pace. It is by necessity a high-level and sparse overview, an attempt to capture the bigger picture without getting dragged down into the details. Watching early stage progress in research from year to year can be a frustrating process, but as senescent cell clearance demonstrates, once a field reaches the tipping point of viability and support, things then move very rapidly.

 

2002

2003

  • The Methuselah Foundation is created, and the founders launch the Mprize for longevity science, a research prize aiming to spur greater interest in extending healthy life spans.
  • The first SENS-focused academic conference is held in the UK under the auspices of the International Association of Biomedical Gerontology.

2004

  • The Methuselah Foundation begins to assemble the 300, a core group of donors who go on to be influential in the course of advocacy and development of rejuvenation biotechnology. Their funds power the early work of the foundation, and some start their own initiatives in later years.

2005

2006

2008

  • The Methuselah Foundation expands allotopic expression funding to support a French research group that will go on to establish Gensight Biologics on the strength of this work. The foundation also announces the commencement of research initiatives for most of the other SENS programs: clearing senescent cells, removing metabolic waste such as amyloid and cross-links, and investigation of alternative lengthening of telomeres (ALT) in the context of cancer.
  • The first US SENS conference is held at UCLA.

2009

  • The SENS Research Foundation spins off from the Methuselah Foundation to focus entirely on SENS rejuvenation research.
  • GSK and Pentraxin Therapeutics begin a collaboration to develop a therapy capable of clearing transthyretin amyloid.
  • The Methuselah Foundation makes its first outside investment in the Organovo tissue printing startup.

2010

  • The SENS Research Foundation's yearly budget reaches $1 million. The foundation sets up a laboratory facility in Mountain View, California for ongoing intramural research projects.
  • Jason Hope pledges $500,000 to the SENS Research Foundation to start a research program aimed at developing a viable cross-link breaker for glucosepane in humans.
  • Researchers find that transplanting a young thymus into an old mouse restores immune function and extends life.

2011

  • Aubrey de Grey devotes the majority of his $16.5M net worth to funding SENS research.
  • The SENS Research Foundation is funding either in-house or external research projects in all of the seven strands of SENS rejuvenation research. Some are very early stage, focused on building tools or discovery, while others are building the basis for therapies.
  • The first demonstration of targeted senescent cell clearance is carried out by an independent research group, producing benefits in mice with an accelerated aging condition.
  • The Methuselah Foundation launches the New Organ tissue engineering initiative.

2012

  • Gensight Biologics is founded to commercialize allotopic expression of mitochondrial gene ND4, based on the research program supported initially by the Methuselah Foundation, and later the SENS Research Foundation.
  • The SENS Research Foundation demonstrates bacterial enzymes that can break down 7-ketocholesterol in cell culture.
  • Methuselah Foundation supported tissue printing company Organovo becomes publicly traded on NASDAQ.
  • Covalent Bioscience is founded to advance work on catalytic antibodies (or catabodies) to clear the amyloid associated with Alzheimer's disease.

2013

  • Gensight Biologics raises a $32M series A round.
  • The Methuselah Foundation announces a $1 million research prize for liver tissue engineering as a part of the New Organ initiative. This year the foundation also fiscally sponsors organ banking initiatives at the Organ Preservation Alliance.
  • The important Hallmarks of Aging position paper is published, the authors taking a cue from the SENS rejuvenation research proposals, but carving out their own view on damage and repair.
  • Google Ventures launches Calico, adding a great deal of support to aging research with the size and publicity of the investment. Unfortunately Calico goes on to focus on areas of aging research unrelated to rejuvenation.
  • Cenexys is founded to work on the creation of means to selectively destroy senescent cells in aged tissues.

2014

  • The Methuselah Foundation and SENS Research Foundation provide seed funding to launch Oisin Biotechnologies, to develop a method of targeted clearance of senescent cells.
  • The SENS Research Foundation begins the Rejuvenation Biotechnology conference series, bringing together industry and academia to smooth the path for development of rejuvenation therapies.
  • Following the Hallmarks of Aging, leading researchers publish their Seven Pillars of Aging position, again echoing the long-standing SENS view of aging and its treatment.
  • The SENS Research Foundation funds development of catabodies to break down transthyretin amyloid, and the work shows considerable promise.
  • Human Rejuvenation Technologies is founded to commercialize a treatment for atherosclerosis based on SENS Research Foundation LysoSENS program approaches to clearing metabolic waste compounds.

2015

  • The SENS Research Foundation's yearly budget reaches $5 million.
  • The Spiegel Lab at Yale announces a method of creating glucosepane, a vital and to this point missing tool needed to develop glucosepane cross-link breaker drugs. This work was funded by the SENS Research Foundation.
  • A research team demonstrates the first senolytic drug candidates capable of selectively destroying senescent cells. The number of candidate drugs increases quite quickly after this point.
  • Pentraxin Therapeutics announces positive results in a trial of targeted clearance of transthyretin amyloid. Meanwhile, evidence continues to emerge from other groups for transthyretin amyloid to have more of an impact in age-related disease that previously thought.
  • SENS Research Foundation work on sabotaging ALT to suppress cancer receives more attention. Meanwhile progress is reported on the other half of telomere extension blockade, interfering in the operation of telomerase, an area in which a number of groups are participating.
  • The Methuselah Foundation makes a founding investment in Leucadia Therapeutics in order to pursue a novel approach to the effective treatment of Alzheimer's disease.
  • The research program producing catabodies capable of breaking down transthyretin amyloid is transferred to Covalent Bioscience for clinical development.

2016

2017

2018

  • The influential Y Combinator venture firm launches YC Bio, aimed squarely at funding startups working on the treatment of aging. There are now at least five venture funds dedicated to investing in startups that work on the treatment of aging as a medical condition.                   

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What are you without the sum of your parts?

#7
Hyndal_Halcyon

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Although I haven't really read the actual stuff and also didn't mention it, I'm a HUGE fan of everything high tech, futuristic, speculative, and whatnot from the Quantum Thief series, All Tomorrows, Jakob's Canon, Yuli Ban's Fiction, Foundation series, Jenkinverse, Eldraeverse, Ander's Sandberg's Roleplaying games, a ton of underrated short stories from the HFY subreddit. Name it and I may have already come across it, even picked up whatever concept there is to see. I've also been lurking this place since 5th grade so I'm not really new here but still.

 

I'd like to see science fiction fantasy beyond popular or simply possible. I'm longing for something along the line of posthuman-level stuffs like designer xenobiology, ToE physics, femtotechnology, politics of omnipotence, post-scarcity market structures, soul-centered ethics, morality based on chaos and game theory, etc.

 

Pretty much any illustration of a world that has reached the ceiling of technology and culture is something new.


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As you can see, I'm a huge nerd who'd rather write about how we can become a Type V civilization instead of study for my final exams (gotta fix that).

But to put an end to this topic, might I say that the one and only greatest future achievement of humankind is when it finally becomes posthumankind.


#8
wjfox

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Have you read Iain Banks' Culture series?


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#9
zEVerzan

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Yes, Culture! A progressive's rebuttal to Space Opera, which is usually very conservative in its ideas and application of technology to storytelling.


I always imagined the future as a time of more reason, empathy, and peace, not less. It's time for a change.
Attention is currency in the "free marketplace of ideas".
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#10
Jakob

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 I've also been lurking this place since 5th grade so I'm not really new here but still.

If you're 20 now, I don't think this place existed when you were in 5th grade. The site is only 8 years old, unless you're talking about the old forum.

 

 

I'd like to see science fiction fantasy beyond popular or simply possible. I'm longing for something along the line of posthuman-level stuffs like designer xenobiology, ToE physics, femtotechnology, politics of omnipotence, post-scarcity market structures, soul-centered ethics, morality based on chaos and game theory, etc.

Ah, yes, this is all stuff that I'm intrigued by too. Though as you may know, I tend use the juxtaposition of such things with everyday life as a source of humor.

 

 

Pretty much any illustration of a world that has reached the ceiling of technology and culture is something new.

Ah, I have one of those projects too. It's called The Man Who Moved the Stars. If only I could separate myself from my work and write a decent self-deprecating satire instead of emoing around like a 14 year old girl on Tumblr, it would be brilliant. But I've had difficulty doing that, so it remains on hold.

 

On another note, would you be interested in some sort of collaboration (not necessarily on TMWMTS, just in general).



#11
Sciencerocks

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I am really hoping for some anti-aging breakthrough or a cure for cancer...Other then that we need a cheaper way to get into space and I am currently watching space-x for the solutions.

 

Honestly what really matters is living longer, feeling good and getting humanity the fuck off this planet.



#12
kjaggard

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you want a new perspective on human futures look at things like 

Accelerando

 By charles stross, and the works of Cordwainer Smith 


Live content within small means. Seek elegance rather than luxury, Grace over fashion and wealth over riches.
Listen to clouds and mountains, children and sages. Act bravely, think boldly.
Await occasions, never make haste. Find wonder and awe, by experiencing the everyday.

#13
Teal

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Here is something new

 

We will have never have AI with a equivalent intelligence of humans and most people here are delusional


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#14
wjfox

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We will have never have AI with a equivalent intelligence of humans

 

 

Why not? Is there some magic or fundamental law of the universe that prevents this?

 

Maybe it's you that's delusional? Computers in 2100 will be quadrillions of times more powerful than today. And they'll begin to design themselves long before then.


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#15
rennerpetey

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Here is something new

 

We will have never have AI with a equivalent intelligence of humans and most people here are delusional

I disagree, but I'm willing to listen to why you think that way.


John Lennon dares you to make sense of this

Spoiler

#16
zEVerzan

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We will have never have AI with a equivalent intelligence of humans and most people here are delusional

 

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I always imagined the future as a time of more reason, empathy, and peace, not less. It's time for a change.
Attention is currency in the "free marketplace of ideas".
I do other stuff besides gripe about the future! Twitter Youtube DeviantArt +-PATREON-+




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