The Transhumanists Who Want to Live Forever
Given these clues, Clement is expanding his medicine cabinet of pills. So far he has financed and supervised four small studies, in volunteers, of treatments found to extend the healthy lives of rodents—the immune drug rapamycin, the supplement NAD+, a combination of compounds that kill off aged cells, and injections of plasma concentrated from umbilical cords. His aim is “to do as many small trials as possible” to generate and publish basic information on safety and possible benefits. With that, he says, people interested in life extension “can decide to take the risk.”
Good for him. I should probably read more what this guy is up to.
As I said before, we need to revise the role of the FDA, so that people can experiment with drugs that are now considered off-limits (unless you are unhealthy).
“I think anybody under 50 who does not have a genetic liability will make it to longevity escape velocity.”
That's good to hear -- though, I might have some "genetic liabilities". Based on lab test results, I am in perfect health; probably the top 10 percentile, healthwise, and maybe even top 2 percentile. I don't have high blood pressure, diabetes, or heart disease; and various tests I took indicate that my risk of development any of them is pretty low.
One thing mentioned:
After Kirkland showed that another drug, called fisetin, makes mice fed it live about 20% longer, self-experimenters didn’t delay in trying it. “The Mayo clinic protocol called for 180mg, but I decided to [hit] those zombie cells harder,” read a post I found on the Age Reversal Network, a bulletin board that’s a hotbed of longevity tips.
I looked into fisetin. Unfortunately, it's hard to get a lot of it in supplement form -- and you need a lot of it, because it has low bioavailability. One solution would be to find a better way to extract it or produce it; another would be to find some way to enhance the bioavailability (e.g. via injection or patch).