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Anti aging thread


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#81
starspawn0

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One thing David Sinclair mentions in the above talk, but doesn't answer, is the following: if you age the brain of mice, does the epigenetic clock of other parts of the body age as well. In other words, are the clocks all coupled so tightly that aging in one organ affects the others?

If the answer is "yes", and if it also works in reverse, so that de-aging one organ somewhat de-ages the others (partially resets their clocks), then that would be a way to greatly slow aging! Basically, replace several organs with 3D-printed "young" copies; then, over time, all the other organs will become younger, too.

Perhaps, assuming that recent paper on HGH-induced age-reversal pans out, this is the cause: HGH caused the thymus to operate like when the person was young; which, in turn, caused the immune system to de-age (as measured by epigenetic clock).
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#82
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https://mobile.twitt...046160480722944

You are looking at the #future. A device that will soon look like small bandaid & measure 100s of biomarkers, telling you what’s best to eat & when to get to the doctor, pushing diseases & frailty off into the future. #health #OptimalHealth #tech #fitness


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#83
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From 2016: might be a way to protect DNA from reactive oxygen species:

https://www.newscien...ld-for-its-dna/

Given that DNA damage is claimed to be a major cause of aging (by David Sinclair), this might have life-extension effects.
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#84
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Researchers Identify Cells that Drive Human Skin Aging

https://discoverysed...man-skin-aging/

Just think:. Senolytics could be a way to keep people looking young, by virtually eliminating wrinkles and other signs of skin aging.

Three authors report that they are employees of Unilever and state, “although no products were tested, this work could potentially promote the use of anti-aging products and lead to financial gain for Unilever.”


That's an understatement!

#85
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Perhaps this should be considered medical news, but I have a future sci-tech angle on it:
 
https://spectrum.iee...work-heart-rats

Bionic Pacemaker Controlled by Neural Network Reverses Heart Failure in Rats

....

In a paper published this week in the Journal of Physiology, Paton and his colleagues describe a smarter pacemaker that puts natural variation back into a failing heart, helping it to work more efficiently.

The device reads the electrical signals generated by each breath, and paces the heart accordingly. In rats with heart failure, the device increased the amount of blood their hearts could pump by 20%, compared with monotonic pacemaking, according to the study.


Might work in people. Here's my future take: why not do this for other organs, too, like the kidneys and liver? e.g. the body has ways of estimating how much insulin it will need, but sometimes it guesses wrong. What if by using deep neural nets that take in sensory input, they can stimulate and inhibit organs to where they react more efficiently? I bet it's possible. ​

#86
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https://youtu.be/E-IaSS0bbGU

Nov 14, 2019
Investor and entrepreneur Peter Thiel delivers the 2019 Wriston Lecture.

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Peter Thiel is 52 years old. He looks 22 years old. 






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