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Complex organ replacements grown from stem cells by 2020 too optimistic?


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#21
Italian Ufo

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Question is - are we talking about technical possibility or regular procedures.


The timeline says that "The economic benefits are huge" so this can be interpreted as it became a regular procedure.
For how much I agree on many things with WJFOX I dont think this would be possible by 2020. I know well how medical reserch works. My prediction is that If we are lucky we may inject stem cells to minimize and possibly partly repair the damages of hearth failures in 2020. But making an entire heart engineered from stem cells ...dream about it.

Edited by Italian Ufo, 25 May 2012 - 12:06 AM.


#22
Logically Irrational

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Not too optimistic at all.

http://www.zeitnews....art-muscle.html


Did you read well the article ?: "The technique had been tested only on rats and it seemed decades could pass until it would become suitable for humans".
As I said, For reserch purposes I have worked with pepole that is experimentig stem cells on heart. The vast majority says that this technology will be available years and years from now.


Oddly enough, the context of that quote says the opposite.

Another breakthrough in biology and medicine was reported, as scientists were able, for the first time, to take skin cells from patients who had suffered heart failure and make them repair the cardiac muscle.

The technique had been tested only on rats and it seemed decades could pass until it would become suitable for humans, but in lack of anything better, doctors applied it, and it worked out remarkably fine, marking the beginning of a new era in the quest for replacement cells to treat tissue affected by disease, Israeli researchers declared.


The technique had seemed decades off, until this procedure was done. Now that the procedure has been done successfully, it appears much more feasible than it once did.
Ph'nglui mglw'nafh Cthulhu R'lyeh wgah'nagl fhtagn!

#23
Italian Ufo

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Not too optimistic at all.

http://www.zeitnews....art-muscle.html


Did you read well the article ?: "The technique had been tested only on rats and it seemed decades could pass until it would become suitable for humans".
As I said, For reserch purposes I have worked with pepole that is experimentig stem cells on heart. The vast majority says that this technology will be available years and years from now.


Oddly enough, the context of that quote says the opposite.

Another breakthrough in biology and medicine was reported, as scientists were able, for the first time, to take skin cells from patients who had suffered heart failure and make them repair the cardiac muscle.

The technique had been tested only on rats and it seemed decades could pass until it would become suitable for humans, but in lack of anything better, doctors applied it, and it worked out remarkably fine, marking the beginning of a new era in the quest for replacement cells to treat tissue affected by disease, Israeli researchers declared.


The technique had seemed decades off, until this procedure was done. Now that the procedure has been done successfully, it appears much more feasible than it once did.


Yes you are right, I didnt read the sentence well. it can happen since English is not really my first language. But I believe of what I believe and it is also based on personal experience. One should read more than one article and not making a claim on one of few resources. Online it is full of medical articles that contradict the prediction.
Furthermore, in the 1990s they said that by 2008 HIV would be cured where are we now? history teach us things even if sciences moves a bit faster today.

#24
Logically Irrational

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Yes you are right, I didnt read the sentence well. it can happen since English is not really my first language. But I believe of what I believe and it is also based on personal experience. One should read more than one article and not making a claim on one of few resources. Online it is full of medical articles that contradict the prediction.
Furthermore, in the 1990s they said that by 2008 HIV would be cured where are we now? history teach us things even if sciences moves a bit faster today.


Fair enough. I was just pointing out a mistake I saw. Personally, I'm of two minds as to how this will go. What I'm interested in is seeing some genuine scientific studies. Not reports on them but the actual papers themselves. Based on what I've searched for, news articles have appeared split even way. I know you say you have personal accounts. Any chance they have some kind of published work on the subject?
Ph'nglui mglw'nafh Cthulhu R'lyeh wgah'nagl fhtagn!

#25
Italian Ufo

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There are many questions that need to be answered. For example, how long will the replacement cells continue to function? and even when we have experiments with mie do the rodent research models accurately reflect human heart conditions and transplantation responses? Do these new replacement cardiomyocytes derived from stem cells have the electrical-signal-conducting capabilities of native cardiac muscle cells? I mean this and other questions are hard to be answered precisely in such a short time.

#26
wjfox

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There are many questions that need to be answered. For example, how long will the replacement cells continue to function?


Method Discovered to Stop Stem Cell Aging

http://extremelongev...tem-cell-aging/

#27
MarcusAurelius

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Yes you are right, I didnt read the sentence well. it can happen since English is not really my first language. But I believe of what I believe and it is also based on personal experience. One should read more than one article and not making a claim on one of few resources. Online it is full of medical articles that contradict the prediction. Furthermore, in the 1990s they said that by 2008 HIV would be cured where are we now? history teach us things even if sciences moves a bit faster today.

Fair enough. I was just pointing out a mistake I saw. Personally, I'm of two minds as to how this will go. What I'm interested in is seeing some genuine scientific studies. Not reports on them but the actual papers themselves. Based on what I've searched for, news articles have appeared split even way. I know you say you have personal accounts. Any chance they have some kind of published work on the subject?


I was pretty sure the first time that the source was accurate.

Anyways here is another link. This time to do with artificial organs, which i think will go hand in hand with the rapid advancement of organ replacement either by stem cell research or other means.

http://www.zeitnews....cial-heart.html

#28
Italian Ufo

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Here is a link of some pepole I know and that has been involved in the study of heart regeneration via stem cells.

http://www.creges.ca...emcells2011.pdf

#29
Italian Ufo

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Yes you are right, I didnt read the sentence well. it can happen since English is not really my first language. But I believe of what I believe and it is also based on personal experience. One should read more than one article and not making a claim on one of few resources. Online it is full of medical articles that contradict the prediction. Furthermore, in the 1990s they said that by 2008 HIV would be cured where are we now? history teach us things even if sciences moves a bit faster today.

Fair enough. I was just pointing out a mistake I saw. Personally, I'm of two minds as to how this will go. What I'm interested in is seeing some genuine scientific studies. Not reports on them but the actual papers themselves. Based on what I've searched for, news articles have appeared split even way. I know you say you have personal accounts. Any chance they have some kind of published work on the subject?


I was pretty sure the first time that the source was accurate.

Anyways here is another link. This time to do with artificial organs, which i think will go hand in hand with the rapid advancement of organ replacement either by stem cell research or other means.

http://www.zeitnews....cial-heart.html


Yes in Italy we do lots of experiments with stem cells for heart regeneration. If you look at the link above you will see that we are between the top countries. In Palermo, Sicily they even opened a stem cells factory which concentrates for the large part on heart regeneration. In 2007 they said that by 2013 they would have gone directly to patients not it become after 2020 according to their last interview. I think the most reliable resoures are scientific publications where methods, explications, long-term patient observation and results are explained in detail.
Articles on internet are often deceptive especially in medical fields.

#30
MarcusAurelius

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Another link that might be of interest. On our quest to an organ replacement future.

http://extremelongev...ith-stem-cells/

http://extremelongev...cial-intestine/

http://extremelongev...oves-blindness/

http://extremelongev...cial-intestine/

Edited by MarcusAurelius, 29 May 2012 - 07:13 PM.


#31
Italian Ufo

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Another link that might be of interest. On our quest to an organ replacement future.

http://extremelongev...ith-stem-cells/

http://extremelongev...cial-intestine/

http://extremelongev...oves-blindness/

http://extremelongev...cial-intestine/


Thanks, I just hope the sooner, the better. There are lots of pepole who are willing and waiting to improve their quality of life.

Edited by Italian Ufo, 29 May 2012 - 09:40 PM.


#32
Zeitgeist123

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hmm. seems like there really are no big reasearch with height increase for adults via gene therapy or stem cell. they could probably make a fortune out of it, especially that global money are going in asia.

“Philosophy is a pretty toy if one indulges in it with moderation at the right time of life. But if one pursues it further than one should, it is absolute ruin." - Callicles to Socrates


#33
MarcusAurelius

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hmm. seems like there really are no big reasearch with height increase for adults via gene therapy or stem cell. they could probably make a fortune out of it, especially that global money are going in asia.


I presume that your proposition is alot harder to achieve in the medical world. It is also of a lesser priority than say a cure for cancer and organ replacement research. However once a persons growth plate bones fuse there is little that the body can do anyways. My guess is that any attempts to formulate some grow taller product based on stem cell or gene therapy would have to regress your bone growth plates to that of an adolescent and then increase cell division in those areas as is the natural state of any healthy teenage individual. Then we might see some major leaps in that area of technology. But I think we will likely see fully approved stem cell penile enlargements a reality before we see height increase. I hazard a guess that this is the biggest untapped and lucrative market that can see realistic results within the next decade or so, as well as natural stem cell derived breast augmentation for women. That will surely take over the silicon breast market literally overnight. We might see height augmentation therapies derived from gene or stem cell treatment after these other milestones become a reality. But I don't think anybody is holding their breath to that one.

#34
Italian Ufo

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Mean while in a ortopedic hospital in Bologna are making an experiment with platlet rich plasma to increase eight. Basiclly part of the tibia is cut and then a scafold is put in that area and fuse with biological screws which will aborb along with the scaffold 2 months later. Platlets are injected inside of the are and bone tissue starts to form. it is a very painful procedure that may also require the wheel chair for 2 months. It is also done in very selected case especially for pepole who can be categorize as Dwars. It is an experimenta procedure. However height increase is not new. A family friend was born with a leg longer than the other and as she growth she had to repeat the surgery by implanting artificial bones. A gene thearpy or stem cells therapy for height increase is still many years away.

#35
wjfox

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Slightly misleading headline, but interesting story nonetheless. FTA: "The cells grew into a human liver five millimetres in size that was capable of generating human proteins and breaking down drugs."

---

Japan team creates liver from stem cells

Japanese scientists have created a functioning human liver from stem cells, according to a newspaper report.

The development, announced on Friday, raises hopes for the manufacture of organs for transplants.

A team of scientists transplanted induced pluripotent stem (iPS) cells into the body of a mouse. They grew into a small, but working, human liver, the Yomiuri Shimbun newspaper said.

http://news.msn.co.n...from-stem-cells

#36
Craven

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I'd say it's a great start :)
"I walk alone and do no evil, having only a few wishes, just like an elephant in the forest."

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#37
Italian Ufo

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http://www.reuters.c...069953820070530

See this article. The experiment went very well but I am not aware that it was replicated after than.

Anyway lets hope this techniques increase. It would be a bless for us with some health issues.

#38
Anu

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http://www.reuters.c...069953820070530

See this article. The experiment went very well but I am not aware that it was replicated after than.

Anyway lets hope this techniques increase. It would be a bless for us with some health issues.


i tink it will
as for the topic i believe that complex organ grown from stem cell's will be possible in the next decade, the progress is being fast in here if not on the next decade it will surely be avaible on the 30's

#39
Italian Ufo

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From 2030 and on than we start to reason...something will be possible but still things will be under scrupolus observation.

#40
msanta89

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It likely will be available by 2020, at least to some extent. However the cost will likely be astronomical and only the wealthiest will be able to afford it. But by 2030 or 2040 it will almost certainly be more affordable to the average person.




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