One handicap to doing "ancestor simulations" to understand past events better is that it would be unethical to create "virtual humans" who would suffer and die inside a computer. But here's a possible solution: have AIs and posthumans voluntarily stand-in for the virtual humans in the simulations.
Here's how it would work: Assume that the year is 2219, and not 2019. You aren't actually "you"--you are either a posthuman lying in a Matrix pod or an AGI. In either case, you agreed to have your memories temporarily blocked and your personality temporarily altered so you could live a lifetime as your current "human" self inside a computer simulation of Earth, circa 2019. After careful thought, you agreed to bear the burden of suffering for one human lifetime, for the sake of supporting a realistic ancestor simulation, and because you thought the experience of being "human" would enrich your understanding of the universe and make you more grateful for what you have. After your virtual human character dies in the simulation, you will be revived in the real world of 2219, and have your old memories and personality traits restored. However, you will also retain the qualities of the virtual human you once were.
This would solve the "suffering" problem since no virtual humans would need to be created. Only posthumans and AGIs who had the strength of character and selflessness to endure one human lifetime of suffering would be in the simulation.