A Wall Street Journal piece about "Intermittent Fasting" (say, only eating in a narrow sliver of time each day; and not eating more than 14 hours each day):https://www.wsj.com/...fad-11564676512
It mentions evidence from lab animals and a few human trials that it helps fight: diabetes, weight gain, Parkinson's, Alzheimer's, Multiple Sclerosis, liver disease, pancreatic disease, and cancer; in many cases, the effect is very large. Furthermore, there is evidence that it improves cognitive functioning, and also autophagy, which is the body's own natural senolytics. In combination with NAD+ boosters (like Nicotinamide Riboside) and/or protein-restriction, it may have a powerful anti-aging effect.
As I've said before, I do intermittent fasting -- eating all my meals (usually just 2) in about a 6 to 7 hour sliver of time each day. I have found, though, that it leaves me dehydrated -- you have to force yourself to drink more water, if you drop one meal per day (you consume liquids naturally and easily with meals; but if you don't eat one, then you have to find a way to fill that "hydration gap"). I also usually drink a protein shake, to make sure I get adequate protein (dropping one meal also drops protein intake).
Intermittent fasting is a lot easier to pull off that most people imagine. If one starts slow -- say, reducing the size of one meal until it's gone -- and then moves the remaining meals closer and closer to the same time of day, one can reprogram ones body to where one won't get hungry, while making the fasting a "habit", part of ones daily routine. Once one has done that, it actually takes effort not
to fast -- it just feels weird to eat outside of those special hours.But, of course, I'm speaking about people with average human physiology. This might not apply to people with autoimmune disorders, metabolic disorders, and even psychosomatic disorders.
(I am reminded of how, when giving lectures to a large class in which I use the word "you", and what is said after applies to 98% of the class, but not to one or two precocious students. The precocious student [sometimes borderline autistic or "different" in some way, but brilliant] thinks I've just made an error, and gets nonplussed about my making assumptions about "them". Ahhh, but they are blissfully unaware that I've not; and that it's just more expedient not to be too nuanced in the message.)