In the previous discussions of the 2045 project I've made this argument but I'll say it again:
In all likelyhood what they will get is a sort of telepresence set up by early to mid 20s. But upon trying to push further they will hit some very major hurdle.
By late 40s I expect the first brain into artificial body will be attempted, and I also expect that three months will be the total lifespan of that experiment. The discovery will be that they really just have no idea how to keep a brain viable long term outside the complex chemical and electrical systems of the body. There will be at least three more attempts before they get somebody to survive more than a year or two, and that person will likely have severe intellectual impairment and possibly a psychotic episode. Again the complex chemical environment and biorythms are far more subtle than we can anticipate.
It's far more practical to find ways to jack somebody into a VR setup and whittle away an aging body bit by dieing bit. Replacing systems with smaller systems that perform similar functions until you have a shell like a beachball with brain and life support while the person lives full time in VR. Eventually we may see coming back out in some forms of robotics but it's going to take a good long while before a realistic human body can be made.
For me the last two ideas are foolish pipe dreams that we will learn before then simply won't be possible anymore than the idea of shrink rays and genetically engineering x-ray vision.
The more important thing though is the spin offs that result and the hacks that happen when even pars of these techs start to get realized. Mind controlled devices, cybernetics, robotic augmentation and body modification. Body swapping, animal mimicry, tricks the human body just can't do, and people becoming ships and buildings if they choose.
It'll be far more amazing than they anticipate, and so I hope they try for all they are worth. Because even getting just short of half way there would be enough to completely change the way the world is.