Once we accomplish and automate everything, we will have nothing else to do, just like in Minecraft.
In the game, the main thing you do is build, and improve upon the stuff you build (and fighting monsters, but that is besides the point). Then you build mechanisms using redstone, and improve on them.
Kind of like what our beings are like. We build buildings, and improve on them, making them more efficient, more aesthtically pleasing. Then we build computers, and improve them to make them faster, cheaper, etc. What will become of us when we have accomplished everything and there is literally nothing else we can do to make out lives easier. We would invent things that, today, we couldn't even imagine; we needn't explore everything because we have all that knowledge already.
I can just imagine universes where there are just entities floating around, nonchalanty, simulating universe-ception in their minds....