If I could run nasa the way I'd like to(man program)
Goal 1. simply make surface to orbit cheap and reusable. I'd focus on helping Eon musk and his grasshopper concept expand into that vehicle. Goal should be 1/10th current price or better. By 2020 this would go to orbit with humans all the way to the space station like the current dragon ship. Focus on this = success.
Goal 2. Build a "work horse" space ship that is modeled after our navy ships/international space station. You wouldn't build a ship within the navy just to throw it away after one time, would you? Nor should we be doing so now. I'd simply use the bigelow inflated module concept with 2-3 lined up for the human environment attached to a ion engine that can be reused over and over again. Maybe a solar sail for mars missions... https://en.wikipedia...ace_Station.jpg http://cdn.zmescienc...-iss-module.jpg
This idea would be far cheaper and would be reusable hundreds of times if need be.
Goal 3. Help build the space station in the above link. Much cheaper but roomy then the current international space station. 20-24 people could fit within 4-5 modules.
Goal 4. Use our space ship in 2. to go to the moon and mars We wouldn't have to worry about building a new ship every time we wanted to go some where = much cheaper.
Of course I'd carry on with our robotic/probe line up we currently have