Aging & Longevity News and Discussions

[wjfox]

Xi Muses on Living to 150 in Hot-Mic Moment With Putin, Kim

September 3, 2025

Chinese President Xi Jinping commented on the possibility of people living to 150 during a hot-mic moment with his Russian and North Korean counterparts, a rare glimpse of an unscripted chat between three of the world’s most prominent strongmen.

The conversation between Xi, Vladimir Putin and Kim Jong Un was captured on a live feed as the leaders ascended the Tiananmen Gate in Beijing, where they would observe a ceremony marking the 80th anniversary of Japan’s defeat in World War II on Wednesday. It was first flagged by social media users watching festivities around China’s military parade.

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A translator then appeared to relay the Russian leader’s remarks, saying in Mandarin: “With the development of biotechnology, human organs can be continuously transplanted, and people can live younger and younger, and even achieve immortality.”

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Xi then spoke again in Mandarin in the final comment as the camera cut away: “Predictions are, this century, there’s a chance of also living to 150.”

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Modern medical developments including surgery to replace organs give rise to expectations that “life expectancy will increase significantly,” Putin said. “This will have social, political and economic consequences. Of course we should also think about this.”

https://www.bloomberg.com/news/articles ... -putin-kim

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[firestar464]

Study of the world's longest-lived person reveals rare genes and good bacteria are among the keys to a long life

https://phys.org/news/2025-09-world-lon ... -rare.html

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Polyunsaturated fatty acid therapy reverses age-related vision decline in mice

https://medicalxpress.com/news/2025-09- ... erses.html

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[firestar464]

‘To them, ageing is a technical problem that can, and will, be fixed’: how the rich and powerful plan to live for ever

https://www.theguardian.com/lifeandstyl ... e-for-ever

The cost of giving so much to the technofundamentalist dream of AI immortality has been that resources have been allocated away from initiatives that support people who are getting older today. The administration proposed cuts of hundreds of billions of dollars to Medicare – the social support network for healthcare for millions of US citizens over the age of 65 – and cancelled the White House Conference on Ageing, a flagship event held every 10 years since 1961 to determine the strategic direction for policy to support older Americans.

Truly, all of this radical technological and governance innovation will not help the rest of us live longer, healthier lives.

For the immortalists of Silicon Valley and the rich and the powerful like Xi and Putin, death is not considered an inevitability. Although organ transplantation for eternal life is science fiction, they do have a head start in the race to longevity escape velocity, simply because they can afford cutting-edge treatments, personalised protocols, and as much young blood as they can morally handle. They can live on: as kingmakers, rulers of the world, or bits of computer code that carry their essence throughout the cosmos. But as they remodel the world in their image, they promote the myth that human beings are only as complex as computer code. These are the ideas that are laying the groundwork for an eternal for ever. But we do have a choice about whether to accept them – or to live in the here and now.

Why can't we reject idiot techbros, support older people, AND do longevity research? These aren't necessarily mutually exclusive.

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‘To them, ageing is a technical problem that can, and will, be fixed’: how the rich and powerful plan to live for ever

https://www.theguardian.com/lifeandstyl ... e-for-ever

The cost of giving so much to the technofundamentalist dream of AI immortality has been that resources have been allocated away from initiatives that support people who are getting older today. The administration proposed cuts of hundreds of billions of dollars to Medicare – the social support network for healthcare for millions of US citizens over the age of 65 – and cancelled the White House Conference on Ageing, a flagship event held every 10 years since 1961 to determine the strategic direction for policy to support older Americans.

Truly, all of this radical technological and governance innovation will not help the rest of us live longer, healthier lives.

For the immortalists of Silicon Valley and the rich and the powerful like Xi and Putin, death is not considered an inevitability. Although organ transplantation for eternal life is science fiction, they do have a head start in the race to longevity escape velocity, simply because they can afford cutting-edge treatments, personalised protocols, and as much young blood as they can morally handle. They can live on: as kingmakers, rulers of the world, or bits of computer code that carry their essence throughout the cosmos. But as they remodel the world in their image, they promote the myth that human beings are only as complex as computer code. These are the ideas that are laying the groundwork for an eternal for ever. But we do have a choice about whether to accept them – or to live in the here and now.

Why can't we reject idiot techbros, support older people, AND do longevity research? These aren't necessarily mutually exclusive.

I think we should develop a cure for aging and give it out to all. Seriously, the benefits to society will make it worth it.

[firestar464]

DNA repair mechanisms help explain why naked mole-rats live a long life

https://phys.org/news/2025-10-dna-mecha ... -rats.html

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Restoring youthful microvascular function to aging skin
https://medicalxpress.com/news/2025-10- ... -skin.html
by Justin Jackson, Medical Xpress

The New York University School of Medicine and collaborators found that capillary-associated macrophages in skin decline with age, weakening microvascular repair and reducing perfusion in mice, with skin restoration possible after boosting local macrophage renewal with a growth factor treatment.
Aging of capillary niches

Macrophages occupy distinct tissue niches that coordinate repair and function. Previous studies have linked age-related decline in the density of capillaries to conditions including chronic wounds and neurodegeneration.

[wjfox]

Learning Another Language May Slow Brain Aging, Huge New Study Finds

November 11, 2025

Speaking multiple languages could slow down brain ageing and help to prevent cognitive decline, a study of more than 80,000 people has found.

The work, published in Nature Aging on 10 November, suggests that people who are multilingual are half as likely to show signs of accelerated biological ageing as are those who speak just one language.

“We wanted to address one of the most persistent gaps in ageing research, which is if multilingualism can actually delay ageing,” says study co-author Agustín Ibáñez, a neuroscientist at the Adolfo Ibáñez University in Santiago, Chile. Previous research in this area has suggested that speaking multiple languages can improve cognitive functions such memory and attention, which boosts brain health as we get older. But many of these studies rely on small sample sizes and use unreliable methods of measuring ageing, which leads to results that are inconsistent and not generalizable.

“The effects of multilingualism on ageing have always been controversial, but I don’t think there has been a study of this scale before, which seems to demonstrate them quite decisively,” says Christos Pliatsikas, a cognitive neuroscientist at the University of Reading, UK. The paper’s results could “bring a step change to the field”, he adds.

They might also “encourage people to go out and try to learn a second language, or keep that second language active”, says Susan Teubner-Rhodes, a cognitive psychologist at Auburn University in Alabama.

https://www.scientificamerican.com/arti ... udy-finds/

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[firestar464]

"soon" being a decade

[wjfox]

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Natural compound rejuvenates aging cells in just 28 days
By Bronwyn Thompson
November 16, 2025

https://newatlas.com/diet-nutrition/ant ... une-cells/
Researchers have demonstrated how a secret weapon made in the gut, produced by consuming foods like pomegranate and walnuts, can rejuvenate the immune system in middle age, shielding us from cell damage, inflammation and chronic diseases including cancer.

Researchers at Germany's Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, have spent years investigating the metabolite urolithin A (UA), a natural compound that's produced by gut bacteria in response to ingested ellagitannins from foods such as pomegranates, almonds, walnuts and some berries. The new study follows on from a breakthrough in 2022, when the team found that UA induced a biological pathway that rejuvenates the cellular power plants – mitochondria – in T cells, equipping these immune cells with more cancer-fighting might. But it goes far beyond cancer.

"Three years ago, we discovered that urolithin A could powerfully expand a special population of long-lived, anti-tumor T cells in our laboratory models,” said principal investigator Dr Dominic Denk, a physician-scientist at University Medicine Frankfurt. “Our goal was always to translate our findings from the lab into the clinic."

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More on that by SciDaily:

https://www.sciencedaily.com/releases/2 ... 095926.htm

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https://www.biorxiv.org/content/10.1101 ... 8.530532v3