Cancer News and Discussions

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Restoring youth to old immune cells: mRNA therapy turns back the clock

https://www.nature.com/articles/d41586-025-04082-5

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Scientists develop targeted therapy for T-cell lymphomas and leukemias

by Amy Mone, Valerie Mehl, Johns Hopkins University School of Medicine
https://medicalxpress.com/news/2025-12- ... emias.html

Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets TRBC2-positive T-cell cancers, expanding a precision approach they established in 2024 for TRBC1-positive tumors.

The therapy, an antibody-drug conjugate, targets a protein expressed on the surface of T-cell cancers to deliver a cancer cell-killing drug.

The work, published in Nature Cancer, provides a long-sought therapeutic option for half of T-cell lymphomas and leukemias that express the TRBC2 variant of the T-cell receptor.
Challenges in treating T-cell cancers

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Nano-magnets may defeat bone cancer and help you heal
By Malcolm Azania
January 03, 2026
https://newatlas.com/medical-tech/nano- ... help-heal/

In The Uncanny X-Men, Magneto, supervillain and CEO of the Brotherhood of Evil Mutants, wants to destroy humanity – and in the first X-Men movie, aims at forcibly mutating all human beings so that normals no longer exist to discriminate against mutants.

It turns out that Magneto really should have studied oncology, because if he had, he might have learned that magnetism could be an ultimate weapon against cancer. And then, instead of waging war on humanity, all nations would bow before him, the trillionaire controlling the medical establishment (that is, a different sort of supervillain).

That’s probably not what a team of researchers from Brazil and Portugal were thinking when they harnessed magnetic nanomaterials to find a way to stop bone cancer and heal the body in its wake, but it still holds.

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Life-extending prostate cancer drug to be offered to thousands in England

38 minutes ago

A life-extending prostate cancer drug is to be made available to thousands of men in England in a matter of weeks, after a campaign by a patient and a charity.

Abiraterone has been provided on the NHS in Scotland and Wales since 2023 but not in England and Northern Ireland, except in the most severe cases.

The drug is already prescribed for patients in the UK with very advanced prostate cancer that has spread.

But from now on the drug will be available on the NHS in England to high-risk patients whose cancer has not yet metastasised - potentially saving hundreds of lives.

Amy Rylance, assistant director of health improvement at charity Prostate Cancer UK, said the decision was "a momentous, life-saving victory for the thousands of men whose lives will now be saved".

https://www.bbc.co.uk/news/articles/cwywezx86nko



Institute of Cancer Research

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Cancer might evade immune defences by stealing mitochondria

https://www.nature.com/articles/d41586-026-00123-9

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NHS cancer gene database to identify patients at risk

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A new NHS database of genes linked to cancer could enable patients and their families in England to find out whether they are at risk of developing the disease.

People will be able to have their genetic information compared to the world-first register of 120 genes known to increase the likelihood of getting cancer, NHS England has said.

Those identified as having an inherited risk will be offered routine check-ups and screening for certain cancers, including breast and prostate cancer. Patients could also be tested to see whether they would respond better to particular treatments, allowing for personalised care.

Health Secretary Wes Streeting said the "life-changing and life-saving" tool would fast-track screening and allow more cancers to be caught sooner.

https://www.bbc.co.uk/news/articles/c62v7l4v7gro

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More on that by Euronews:

https://www.euronews.com/health/2026/01 ... 0treatment.

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Fecal transplant capsules show promising results in clinical trials for multiple types of cancer

https://medicalxpress.com/news/2026-01- ... nical.html

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Newly identified RNA molecule may drive cancer patient survival

https://phys.org/news/2026-02-newly-rna ... tient.html

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https://www.sciencedaily.com/releases/2 ... 112137.htm

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Scientists use RNA nanotechnology to program living cells, opening a new path for cancer cure

https://phys.org/news/2026-02-scientist ... -path.html

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Cancer vaccine shows promise against HPV-related throat tumors in early study

https://www.livescience.com/health/canc ... arly-study