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Re: Aging & Longevity News and Discussions

Posted: Mon Jul 26, 2021 6:59 pm
by weatheriscool
Higher Levels of Omega-3 in the Blood Increase Life Expectancy by Almost Five Years
https://scitechdaily.com/higher-levels- ... ive-years/
A 1% increase in this substance in the blood is associated with a change in mortality risk similar to that of quitting smoking.
Levels of omega-3 fatty acids in the blood are as good a predictor of mortality from any cause as smoking, according to a study involving the Hospital del Mar Medical Research Institute (IMIM), in collaboration with The Fatty Acid Research Institute in the United States and several universities in the United States and Canada. The study, published in The American Journal of Clinical Nutrition, used data from a long-term study group, the Framingham Offspring Cohort, which has been monitoring residents of this Massachusetts town, in the United States, since 1971.

Researchers have found that omega-3 levels in blood erythrocytes (the so-called red blood cells) are very good mortality risk predictors. The study concludes that “Having higher levels of these acids in the blood, as a result of regularly including oily fish in the diet, increases life expectancy by almost five years,” as Dr. Aleix Sala-Vila, a postdoctoral researcher in the IMIM’s Cardiovascular Risk and Nutrition Research Group and author of the study, points out. In contrast, “Being a regular smoker takes 4.7 years off your life expectancy, the same as you gain if you have high levels of omega-3 acids in your blood,” he adds.

2,200 people monitored over eleven years The study analyzed data on blood fatty acid levels in 2,240 people over the age of 65, who were monitored for an average of eleven years. The aim was to validate which fatty acids function as good predictors of mortality, beyond the already known factors. The results indicate that four types of fatty acids, including omega-3, fulfill this role. It is interesting that two of them are saturated fatty acids, traditionally associated with cardiovascular risk, but which, in this case, indicate longer life expectancy. “This reaffirms what we have been seeing lately,” says Dr. Sala-Vila, “not all saturated fatty acids are necessarily bad.” Indeed, their levels in the blood cannot be modified by diet, as happens with omega-3 fatty acids.

These results may contribute to the personalization of dietary recommendations for food intake, based on the blood concentrations of the different types of fatty acids. “What we have found is not insignificant. It reinforces the idea that small changes in diet in the right direction can have a much more powerful effect than we think, and it is never too late or too early to make these changes,” remarks Dr. Sala-Vila.

The researchers will now try to analyze the same indicators in similar population groups, but of European origin, to find out if the results obtained can also be applied outside the United States. The American Heart Association recommends eating oily fish such as salmon, anchovies or sardines twice a week because of the health benefits of omega-3 acids.

Reference: “Using an erythrocyte fatty acid fingerprint to predict risk of all-cause mortality: the Framingham Offspring Cohort” by Michael I McBurney, Nathan L Tintle, Ramachandran S Vasan, Aleix Sala-Vila and William S Harris, 16 June 2021, The American Journal of Clinical Nutrition. DOI: 10.1093/ajcn/nqab195

Re: Aging & Longevity News and Discussions

Posted: Wed Jul 28, 2021 4:47 am
by andmar74
Supercentenarian and remarkable age records exhibit patterns indicative of clerical errors and pension fraud
https://www.biorxiv.org/content/10.1101/704080v2

Re: Aging & Longevity News and Discussions

Posted: Wed Jul 28, 2021 4:11 pm
by wjfox

Re: Aging & Longevity News and Discussions

Posted: Wed Jul 28, 2021 5:27 pm
by andmar74
Sinclair looks amazing at 52..

Re: Aging & Longevity News and Discussions

Posted: Wed Jul 28, 2021 6:50 pm
by raklian
andmar74 wrote: Wed Jul 28, 2021 5:27 pm Sinclair looks amazing at 52..
Whatever he's doing to increase his longevity (or healthspan for the matter) seems to be working. :)

Re: Aging & Longevity News and Discussions

Posted: Thu Jul 29, 2021 6:42 am
by andmar74
https://www.fightaging.org/archives/202 ... life-span/

It is Plausible that Continual Removal of Senescence Cells Would Impair Regeneration and Limit Benefits to Life Span

Re: Aging & Longevity News and Discussions

Posted: Thu Aug 05, 2021 3:17 pm
by wjfox

Re: Aging & Longevity News and Discussions

Posted: Mon Aug 09, 2021 7:34 am
by wjfox
Senescence field has “completely exploded”

August 5, 2021

Aubrey de Grey expects senescence-targeting sector will see Phase 3 trials within “a couple of years”.

https://www.longevity.technology/senesc ... -exploded/

Re: Aging & Longevity News and Discussions

Posted: Wed Aug 11, 2021 6:50 pm
by wjfox

Re: Aging & Longevity News and Discussions

Posted: Wed Aug 11, 2021 7:39 pm
by raklian
Maybe much ado about nothing?